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Key Documents

84739

Sigma-Aldrich

Sulfur trioxide triethylamine complex

technical, ≥95% sulfur basis

Synonym(s):

NSC 68185, NSC 8168, Triethylamine sulfur trioxide complex

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About This Item

Linear Formula:
(CH3CH2)3N · SO3
CAS Number:
Molecular Weight:
181.25
Beilstein:
3993165
MDL number:
UNSPSC Code:
12352116
PubChem Substance ID:
NACRES:
NA.22

grade

technical

Quality Level

Assay

≥95% sulfur basis

form

powder

reaction suitability

reagent type: oxidant

mp

~85 °C

storage temp.

2-8°C

SMILES string

O=S(=O)=O.CCN(CC)CC

InChI

1S/C6H15N.O3S/c1-4-7(5-2)6-3;1-4(2)3/h4-6H2,1-3H3;

InChI key

YYHPEVZFVMVUNJ-UHFFFAOYSA-N

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Application

Reactant for reagent for synthesis of:
  • Anticoagulant and antiplatelet persulfated glycosides or flavonoids containing an oligopolysulfated moiety
  • Narciclasine derivatives for use as anticancer agents
  • Sulfate-conjugated methylprednisolone for use as a colon-specific prodrug
  • Tetrasaccharide substrates of heparanase by glycosylation of disaccharides
  • Synthetic heparin oligosaccharide microarrays for analysis of heparin-protein interactions
  • Dexamethasone 21-sulfate sodium for use as a colon-specific prodrug

Other Notes

Reagent used for the sulfation of alcohols and other compounds

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Pictograms

Corrosion

Signal Word

Danger

Hazard Statements

Hazard Classifications

Skin Corr. 1B

Storage Class Code

8A - Combustible corrosive hazardous materials

WGK

WGK 3

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Effect of hexadimethrine bromide on the conversion of 4-14C-progesterone into aldosterone and corticosterone by rat adrenals.
A G Fazekas et al.
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Journal of molecular endocrinology, 61(2), M27-M39 (2018-03-29)
Resveratrol (RSV) is a polyphenolic compound with antioxidant, anti-inflammatory and anti-aging properties partly associated with sirtuin 1 (SIRT1)-activation in the skin. However, poor water solubility may limit RSV efficacy. This work aimed to clarify the interest of a new synthetic
Irshad Ahmad et al.
International journal of biological macromolecules, 119, 360-368 (2018-07-17)
Currently available anticoagulants for prevention and treatment of thrombosis have several limitations, thus, small organic scaffolds that can dissolve clots in vivo in a dose dependent manner with lesser side effects are highly desirable. Here we report the synthesis of
Tarek M Bedair et al.
Colloids and surfaces. B, Biointerfaces, 181, 174-184 (2019-05-28)
Drug-eluting stents (DESs) have been used for the treatment of cardiovascular diseases including stenosis. However, in-stent restenosis, thrombosis, and delayed re-endothelialization represent challenges for their clinical applications. Here, we demonstrate a novel work to overcome these limitations through surface modification
E.E. Gilbert
Chemical Reviews, 62, 549-549 (1962)

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