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Key Documents

797871

Sigma-Aldrich

Ultrastable fluorescent silica nanobeads

120 nm, lyophilized

Synonym(s):

Fluorescent beads, Fluorescent nanoparticles, Silica nanoparticles

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About This Item

Linear Formula:
SiO2
Molecular Weight:
60.08
UNSPSC Code:
12352302
NACRES:
NA.23

Quality Level

form

powder

particle size

120 nm

fluorescence

λem 590 nm

UV absorption

λ: 570 nm Amax

storage temp.

2-8°C

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Application

The use of labeling or staining agents has greatly assisted the study of complex biological interactions in biology and the fluorescent labeling of biomolecules has been demonstrated as an indispensable tool in many biological studies. By virtue of excellent fluorescence properties the silica nanobeads find application in biological labeling, bioimaging, biosensing etc. Ultrastable particles exhibit a very high resistance to photobleaching and can be used in single-particle imaging as well as in super resolution techniques such as stimulated emission depletion (STED) microscopy.

Pictograms

Health hazard

Signal Word

Danger

Hazard Statements

Precautionary Statements

Hazard Classifications

STOT RE 1 Inhalation

Storage Class Code

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

nwg

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Luminescent nanomaterials for biological labelling
F. Wang, W. B. Tan, Y. Zhang, et al.
Nanotechnology, 17(1), R1-R13 (2006)
Geometrical confinement of quantum dots in porous nanobeads with ultraefficient fluorescence for cell-specific targeting and bioimaging
P-J Chen, S-H Hu, W-T Hung, S-Y Chen, and D-M Liu,
Journal of Materials Chemistry, 22(19), 9568-9575 (2012)

Articles

luorescent nanobeads offer great potential for many applications in both basic and applied research. In the recent past, scientists have been offered a wide range of technical solutions in fluorescence imaging, enabling a significant advancement in fields such as microscopy and diagnostics. However, such optical labels mostly spanned the microscale range and/or suffered from limited optical performance and versatility. Recently, the progress of nanoscience has enabled the fabrication of accurately controlled nanostructures with tailored optical properties, and this is disclosing completely unexplored avenues and exciting possibilities in many research areas.

Biomaterials science involves the design and fabrication of smart materials for studying, directing, or mimicking biology. For successful integration of biomaterials in biological research, a meaningful understanding of biological systems is required.

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