47618

Fmoc-Asp(OtBu)-OH

≥98.0% (HPLC), for peptide synthesis

• Synonym(s): Fmoc-L-aspartic acid 4-tert-butyl ester
• Empirical Formula (Hill Notation): C₂₃H₂₅NO₆
• CAS Number: 71989-14-5
• Molecular Weight: 411.45
• Beilstein: 3635671
• EC Number: 276-251-7
• MDL number: MFCD00037131
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57651040
• NACRES: NA.26

Properties

• product name: Fmoc-Asp(OtBu)-OH, ≥98.0% (HPLC)
• Quality Level: 100
• Assay: ≥98.0% (HPLC)
• form: powder
• optical activity: [α]20/D −24±2°, c = 1% in DMF
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• mp: 148-150 °C (dec.)
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 2-8°C
• SMILES string: CC(C)(C)OC(=O)C[C@H](NC(=O)OCC1c2ccccc2-c3ccccc13)C(O)=O
• InChI: 1S/C23H25NO6/c1-23(2,3)30-20(25)12-19(21(26)27)24-22(28)29-13-18-16-10-6-4-8-14(16)15-9-5-7-11-17(15)18/h4-11,18-19H,12-13H2,1-3H3,(H,24,28)(H,26,27)/t19-/m0/s1
• InChI key: FODJWPHPWBKDON-IBGZPJMESA-N

Description

General description

Fmoc-Asp(OtBu)-OH also known as Fmoc-L-aspartic acid 4-tert-butyl ester, is a Fmoc protected amino acid, used in solid phase peptide synthesis.

Application

Fmoc-Asp(OtBu)-OH is used to prevent the formation of aspartimide by-products in Fmoc solid phase peptide synthesis.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves