364843
Ethyl glycolate
98%
Synonym(s):
2-Hydroxyacetic acid ethyl ester, Ethyl 2-hydroxyacetate, Ethyl hydroxyacetate
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About This Item
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Quality Level
Assay
98%
form
liquid
refractive index
n20/D 1.419 (lit.)
bp
158-159 °C (lit.)
density
1.1 g/mL at 25 °C (lit.)
SMILES string
CCOC(=O)CO
InChI
1S/C4H8O3/c1-2-7-4(6)3-5/h5H,2-3H2,1H3
InChI key
ZANNOFHADGWOLI-UHFFFAOYSA-N
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General description
Ethyl glycollate is an ester. Microwave spectra of ethyl glycollate and its deuterated species has been reported.
Application
Ethyl glycollate is an important building block for the preparation of medicinal compounds and agrochemicals. It may be used:
- as starting reagent in the synthesis of 2-ferrocenylfuran
- as substrate during the polycondensation of α-hydroxy acids by enzymes and polyethylene glycol (PEG)-modified enzymes
- in the synthesis of poly(PDL-GA) copolymers, via enzymatic catalysis
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
10 - Combustible liquids
WGK
WGK 3
Flash Point(F)
143.6 °F - closed cup
Flash Point(C)
62 °C - closed cup
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Polycondensation of a-hydroxy acids by enzymes or PEG-modified enzymes in organic media.
Journal of Macromolecular Science, Part A: Pure and Applied Chemistry, 32(2), 179-190 (1995)
Copolymers of ethyl glycolate and ?-pentadecalactone: Enzymatic synthesis and solid-state characterization.
Eur. Polymer J., 47(5), 942-948 (2011)
Aldrichimica Acta, 23, 51-51 (1990)
Synthesis of ferrocenyl-substituted heterocycles: the beneficial effect of the microwave irradiation.
Collection of Czechoslovak Chemical Communications, 59(1), 175-185 (1994)
Microwave spectrum, conformational equilibrium and Ab initio computations for ethyl glycolate.
Acta Chirurgica Scandinavica. Supplementum, 46, 1183-1183 (1992)
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