PVP1

Poly(vinylpyrrolidone)–Iodine complex

• Synonym(s): PVP-Iodine, Polyvinylpyrrolidone Iodine, PVP-I, Povadyne^® antiseptic
• CAS Number: 25655-41-8
• MDL number: MFCD00084483
• UNSPSC Code: 51102829
• PubChem Substance ID: 24899316
• NACRES: NA.85

Properties

• form: powder
• solubility: H₂O: 100 mg/mL
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria; fungi; parasites; viruses; yeast
• Mode of action: protein synthesis | interferes
• SMILES string: II.C=CN1CCCC1=O
• InChI: 1S/C6H9NO.I2/c1-2-7-5-3-4-6(7)8;1-2/h2H,1,3-5H2;
• InChI key: CPKVUHPKYQGHMW-UHFFFAOYSA-N

Description

Application

Poly(vinylpyrrolidone)–Iodine complex, or PVP-I, has been used to study microbial decontamination of human donor eyes and the inactivation of infectious hematopoietic necrosis virus.

Biochem/physiol Actions

PVP-1 is used as a slow iodine release formulation that iodinates lipids and oxidizes cell compounds such as tyrosine sidechains. It is used as a carbon nanotube coating agent to improve water solubility.

Other Notes

An iodophor; "tamed iodine."

Keep container tightly closed in a dry and well-ventilated place.

Legal Information

Povadyne is a registered trademark of National Patent Development Corp.

Safety Information

• Pictograms: GHS05,GHS09
• Signal Word: Danger
• Hazard Statements: H315,H318,H411
• Precautionary Statements: P264 - P273 - P280 - P302 + P352 - P305 + P351 + P338 - P332 + P313
• Hazard Classifications: Aquatic Chronic 2 - Eye Dam. 1 - Skin Irrit. 2
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): >212.0 °F - Not applicable
• Flash Point(C): > 100 °C - Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves