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PRMT1

protein arginine methyltransferase 1

Synonyms:
ANM1, HCP1, HRMT1L2, IR1B4
Species:
UniProtKB ID:
Gene ID:
  • Human(3276) Summary: This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. [provided by RefSeq, Dec 2011]
  • Mouse(15469) protein arginine N-methyltransferase 1
  • Rat(60421) protein arginine methyltransferase 1
  • Zebrafish(321974) protein arginine methyltransferase 1
  • dog(476411) protein arginine methyltransferase 1
  • domestic cat(101095389) protein arginine methyltransferase 1
  • Horse(100052097) protein arginine methyltransferase 1
  • cow(520388) protein arginine methyltransferase 1
  • domestic guinea pig(100724273) protein arginine methyltransferase 1
  • naked mole-rat(101721462) protein arginine methyltransferase 1

Custom & Knockdown Gene Products

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Anti-PRMT1 antibody, Mouse monoclonal, clone PRMT1-171, purified from hybridoma cell culture,
Species Reactivity
bovine, canine, chicken, hamster, human, monkey, mouse, rat
Application
ELISA
immunoprecipitation (IP)

western blot
Anti-PRMT1 Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse
Application
western blot
Monoclonal Anti-PRMT1 antibody produced in mouse, clone GT10111, affinity isolated antibody,
Species Reactivity
human, mouse
Application
western blot
Monoclonal Anti-PRMT1 antibody produced in mouse, clone GT779, affinity isolated antibody,
Species Reactivity
human, mouse
Application
immunofluorescence
western blot
Anti-PRMT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
PRMT1 human, recombinant, expressed in E. coli, ≥50% (SDS-PAGE),
Species
human
PRMT1 Active human, recombinant, expressed in baculovirus infected insect cells, ≥70% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human PRMT1,
Species
human
MISSION® esiRNA, targeting mouse Prmt1,
Species
mouse