OGG1
8-oxoguanine DNA glycosylase
Synonyms:
HMMH, HOGG1, MUTM, OGH1
Species:
Human OGG1 (4968), Mouse Ogg1 (18294), Rat Ogg1 (81528), fruit fly Ogg1 (31806), cow OGG1 (520497), domestic cat OGG1 (101091094), dog OGG1 (484666), chicken OGG1 (771001), Thale Cress OGG1 (838775), Zebrafish ogg1 (791194) ...More
UniProtKB ID:
Gene ID:
- Human(4968) Summary: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined. [provided by RefSeq, Aug 2008]
- Mouse(18294) 8-oxoguanine DNA-glycosylase 1
- Rat(81528) 8-oxoguanine DNA glycosylase
- fruit fly(31806) CG1795 gene product from transcript CG1795-RA
- cow(520497) 8-oxoguanine DNA glycosylase
- domestic cat(101091094) 8-oxoguanine DNA glycosylase
- dog(484666) 8-oxoguanine DNA glycosylase
- chicken(771001) 8-oxoguanine DNA glycosylase
- Thale Cress(838775) 8-oxoguanine-DNA glycosylase 1
- Zebrafish(791194) 8-oxoguanine DNA glycosylase
- sheep(101104015) 8-oxoguanine DNA glycosylase
- naked mole-rat(101697522) 8-oxoguanine DNA glycosylase
- domestic guinea pig(100731436) 8-oxoguanine DNA glycosylase
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-8-Oxoguanine Antibody, clone 483.15, ascites fluid, clone 483.15, Chemicon®,
Species Reactivity
human, monkey, mouse, primate, rat
Application
ChIP
ELISA
immunocytochemistry
ELISA
immunocytochemistry
Anti-OGG1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot