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48540-U

Supelco

Bromodichloromethane

analytical standard

Synonym(s):

Dichlorobromomethane

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About This Item

Linear Formula:
BrCHCl2
CAS Number:
75-27-4
Molecular Weight:
163.83
Beilstein:
1697005
EC Number:
200-856-7
MDL number:
MFCD00000824
UNSPSC Code:
77101502
PubChem Substance ID:
329757384
NACRES:
NA.24

grade

analytical standard

CofA

current certificate can be downloaded

packaging

ampule of 1000 mg

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

refractive index

n20/D 1.497 (lit.)

bp

87 °C (lit.)

mp

−55 °C (lit.)

density

1.98 g/mL at 25 °C (lit.)

application(s)

environmental

format

neat

storage temp.

2-8°C

SMILES string

ClC(Cl)Br

InChI

1S/CHBrCl2/c2-1(3)4/h1H

InChI key

FMWLUWPQPKEARP-UHFFFAOYSA-N

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General description

Bromodichloromethane (BDCM) is the most common trihalomethane (THM). It is a disinfection by-product identified in drinking water after chlorination, which appears to be carcinogenic and toxic. THMs are not only found in drinking supplies but are also prevalent in swimming pools, dump sites and fish samples.

Application

Bromodichloromethane may be used as an analytical standard for the determination of the analyte in drinking water and chlorinated seawater samples by chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Signal Word

Danger

Hazard Statements

H302,H315,H318,H335,H351

Hazard Classifications

Acute Tox. 4 Oral - Carc. 2 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

Lot/Batch Number
LRAD0862
LC15433V
LC11774V
LC04769V
LB85507V

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Suvarthi Das et al.
American journal of physiology. Gastrointestinal and liver physiology, 305(12), G950-G963 (2013-10-26)
Recent studies indicate that metabolic oxidative stress, autophagy, and inflammation are hallmarks of nonalcoholic steatohepatitis (NASH) progression. However, the molecular mechanisms that link these important events in NASH remain unclear. In this study, we investigated the mechanistic role of purinergic
Kevin S McDorman et al.
Chemico-biological interactions, 152(2-3), 107-117 (2005-04-21)
Public drinking water treated with chemical disinfectants contains a complex mixture of disinfection by-products (DBPs) for which the relative toxicity of the mixtures needs to be characterized to accurately assess risk. Potassium bromate (KBrO(3)) is a by-product from ozonation of
Ted Lock et al.
Archives of toxicology, 78(7), 410-417 (2004-05-14)
Male F344 rats exposed to bromodichloromethane (BDCM) by gavage at 50 or 100 mg/kg/day for 5 days a week for 28 days excreted large amounts of formic acid in their urine, which was accompanied by a change in urinary pH.
Regina Grazuleviciene et al.
Occupational and environmental medicine, 70(4), 274-282 (2013-02-14)
Congenital anomalies have been inconsistently associated with maternal crude estimated exposure to drinking water trihalomethane (THM). We investigated the relationship between individual THM uptake during the first trimester of pregnancy and congenital anomalies. We estimated maternal THM uptake for 3074
Teresa L Leavens et al.
Toxicological sciences : an official journal of the Society of Toxicology, 99(2), 432-445 (2007-07-28)
Exposure to bromodichloromethane (BDCM), one of the most prevalent disinfection byproducts in drinking water, can occur via ingestion of water and by dermal absorption and inhalation during activities such as bathing and showering. The objectives of this research were to
View All Related Papers

Protocols

US EPA Method 8260: GC Analysis of Volatiles on SPB®-624 after Purge & Trap using "K" Trap, Fast GC Analysis

US EPA Method 8260 describes the analysis of volatile organic compounds in solid wastes and ground waters. This application illustrates the analysis of many compounds commonly analyzed by this method using purge and trap coupled to GC-MS.

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