SML1012

MN-64

≥98% (HPLC)

• Synonym(s): 2-[4-(1-Methylethyl)phenyl]-4H-1-benzopyran-4-one
• Empirical Formula (Hill Notation): C₁₈H₁₆O₂
• CAS Number: 92831-11-3
• Molecular Weight: 264.32
• MDL number: MFCD00829158
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825630
• NACRES: NA.77

Properties

• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: O=C1C2=CC=CC=C2OC(C3=CC=C(C(C)C)C=C3)=C1
• InChI: 1S/C18H16O2/c1-12(2)13-7-9-14(10-8-13)18-11-16(19)15-5-3-4-6-17(15)20-18/h3-12H,1-2H3
• InChI key: PYTOHIUBXSJKQH-UHFFFAOYSA-N

Description

Biochem/physiol Actions

MN-64 is a very potent inhibitor of Tankyrase 1 and 2 (IC₅₀ = 6 and 72 nM, respectively). The compound MN-64 blocks Wnt signaling in HEK293 cells containing a Wnt pathway reporter system.

MN-64 is a very potent inhibitor of Tankyrase 1 and 2.

Features and Benefits

This compound is a featured product for Gene Regulation research. Click here to discover more featured Gene Regulation products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

Safety Information

• Pictograms: GHS06
• Signal Word: Danger
• Hazard Statements: H301
• Precautionary Statements: P301 + P310
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable