SMB00605

Cephapirin sodium

• Synonym(s): Cefapirin sodium, 3-[(Acetyloxy)methyl]-8-oxo-7-{(4-pyridinylthio)acetyl]amino}-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monosodium salt, Cephapirin sodium
• Empirical Formula (Hill Notation): C₁₇H₁₆N₃NaO₆S₂
• CAS Number: 24356-60-3
• Molecular Weight: 445.45
• EC Number: 246-194-2
• MDL number: MFCD07793329
• UNSPSC Code: 12352200
• PubChem Substance ID: 329825076

Properties

• form: powder
• storage condition: (Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.)
• antibiotic activity spectrum: Gram-negative bacteria; Gram-positive bacteria
• Mode of action: cell wall synthesis | interferes
• storage temp.: 2-8°C
• SMILES string: [Na+].CC(=O)OCC1=C(N2[C@H](SC1)[C@H](NC(=O)CSc3ccncc3)C2=O)C([O-])=O
• InChI: 1S/C17H17N3O6S2.Na/c1-9(21)26-6-10-7-28-16-13(15(23)20(16)14(10)17(24)25)19-12(22)8-27-11-2-4-18-5-3-11;/h2-5,13,16H,6-8H2,1H3,(H,19,22)(H,24,25);/q;+1/p-1/t13-,16-;/m1./s1
• InChI key: VGEOUKPOQQEQSX-OALZAMAHSA-M

Description

Biochem/physiol Actions

Cephapirin is a cephalosporin C antibiotic effective against Gram-positive and Gram-negative bacteria including Staphylococcus aureus, Escherichia coli, Klebsiella pneumonia and Proteus mirabilis.

Packaging

25MG

Preparation Note

Cephapirin is soluble in H2O up to approximately 50 mg/mL and slightly soluble in DMSO and MeOH up to approximately 1 mg/mL.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Safety Information

• Pictograms: GHS08,GHS07
• Signal Word: Danger
• Hazard Statements: H315,H317,H319,H334,H335
• Precautionary Statements: P261 - P280 - P284 - P304 + P340 - P305 + P351 + P338 - P342 + P311
• Hazard Classifications: Eye Irrit. 2 - Resp. Sens. 1 - Skin Irrit. 2 - Skin Sens. 1 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable