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SAB4200056

Sigma-Aldrich

Monoclonal Anti-GBP1 antibody produced in rat

~1.0 mg/mL, clone GBP 1B1, purified immunoglobulin, buffered aqueous solution

Synonym(s):

Anti-Guanylate binding protein 1

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About This Item

UNSPSC Code:
12352203

biological source

rat

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

GBP 1B1, monoclonal

form

buffered aqueous solution

mol wt

antigen ~67 kDa

species reactivity

human

concentration

~1.0 mg/mL

technique(s)

western blot: 0.2-0.5 μg/mL using whole extract of human HS68 cells

UniProt accession no.

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GBP1(2633)

Immunogen

human GBP1 fusion protein

Physical form

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Arun Kumar Haldar et al.
mBio, 11(4) (2020-07-30)
Interferon (IFN)-inducible guanylate binding proteins (GBPs) play important roles in host defense against many intracellular pathogens that reside within pathogen-containing vacuoles (PVs). For instance, members of the GBP family translocate to PVs occupied by the protozoan pathogen Toxoplasma and facilitate
Eric Hastie et al.
Oncotarget, 7(38), 61601-61618 (2016-08-18)
Vesicular stomatitis virus (VSV) based recombinant viruses (such as VSV-ΔM51) are effective oncolytic viruses (OVs) against a majority of pancreatic ductal adenocarcinoma (PDAC) cell lines. However, some PDAC cell lines are highly resistant to VSV-ΔM51. We recently showed that treatment
C T Capaldo et al.
Mucosal immunology, 5(6), 681-690 (2012-06-14)
Proinflammatory cytokines induce guanylate-binding protein 1 (GBP-1) protein expression in intestinal epithelial tissues. GBP-1 has been described as influencing a number of cellular processes important for epithelial homeostasis, including cell proliferation. However, many questions remain as to the role of

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