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R8129

Sigma-Aldrich

Renin Substrate Tetradecapeptide porcine

≥97% (HPLC), suitable for LC/MS and MALDI-TOF

Synonym(s):

Angiotensinogen 1-14, Asp-Arg-Val-Tyr-Ile-His-Pro-Phe-His-Leu-leu-Val-Tyr-Ser

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About This Item

Empirical Formula (Hill Notation):
C85H123N21O20
CAS Number:
20845-02-7
Molecular Weight:
1759.01
MDL number:
MFCD00133798
UNSPSC Code:
12352209
PubChem Substance ID:
24899404
NACRES:
NA.26

product name

Renin Substrate Tetradecapeptide porcine, ≥97% (HPLC)

Quality Level

200

Assay

≥97% (HPLC)

form

powder

technique(s)

LC/MS: suitable
MALDI-TOF: suitable

color

white

storage temp.

−20°C

SMILES string

CCC(C)C(NC(=O)C(Cc1ccc(O)cc1)NC(=O)C(NC(=O)C(CCCNC(N)=N)NC(=O)C(N)CC(O)=O)C(C)C)C(=O)NC(Cc2cnc[nH]2)C(=O)N3CCCC3C(=O)NC(Cc4ccccc4)C(=O)NC(Cc5cnc[nH]5)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(C(C)C)C(=O)NC(Cc6ccc(O)cc6)C(=O)NC(CO)C(O)=O

InChI

1S/C85H123N21O20/c1-11-48(10)70(105-78(119)62(35-51-23-27-55(109)28-24-51)100-80(121)68(46(6)7)103-72(113)57(19-15-29-91-85(87)88)94-71(112)56(86)38-67(110)111)82(123)101-64(37-53-40-90-43-93-53)83(124)106-30-16-20-66(106)79(120)98-60(33-49-17-13-12-14-18-49)74(115)97-63(36-52-39-89-42-92-52)76(117)95-58(31-44(2)3)73(114)96-59(32-45(4)5)77(118)104-69(47(8)9)81(122)99-61(34-50-21-25-54(108)26-22-50)75(116)102-65(41-107)84(125)126/h12-14,17-18,21-28,39-40,42-48,56-66,68-70,107-109H,11,15-16,19-20,29-38,41,86H2,1-10H3,(H,89,92)(H,90,93)(H,94,112)(H,95,117)(H,96,114)(H,97,115)(H,98,120)(H,99,122)(H,100,121)(H,101,123)(H,102,116)(H,103,113)(H,104,118)(H,105,119)(H,110,111)(H,125,126)(H4,87,88,91)

InChI key

XJFQCYIFOWHHFN-UHFFFAOYSA-N

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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The intracerebroventricular administration of renin substrate or angiotensin II evokes antinociception in rodents, but the brain sites where most of the renin-angiotensin system peptides act are not yet known. This study describes the antinociceptive effects of microinjecting porcine renin substrate
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