PLA0263

Rabbit anti-Ku70 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

• Synonym(s): 5′-dRP lyase Ku70, 5′-deoxyribose-5-phosphate lyase Ku70, 70 kDa subunit, 70 kDa subunit of Ku antigen, 70kDa, ATP-dependent DNA helicase 2 subunit 1, ATP-dependent DNA helicase II, ATP-dependent DNA helicase II 70 kDa subunit, CTC box binding factor 75 kDa subunit, CTC box-binding factor 75 kDa subunit, CTC75, CTCBF, D22S671, D22S731, DNA repair protein XRCC6, G22P1, KU70, Ku autoantigen, Ku autoantigen p70 subunit, ML8, TLAA, Thyroid-lupus autoantigen, X-ray repair complementing defective repair in Chinese hamster cells 6, lupus Ku autoantigen protein p70, thyroid autoantigen 70kD (Ku antigen), thyroid autoantigen 70kDa (Ku antigen), thyroid-lupus autoantigen p70
• UNSPSC Code: 12352203
• NACRES: NA.41
• species reactivity: human
• application: IP; WB
• technique(s): immunoprecipitation (IP): 2-5 μg/mg; western blot: 1:2,000- 1:10,000
• citations: 1

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• grade: Powered by Bethyl Laboratories, Inc.
• species reactivity: human
• technique(s): immunoprecipitation (IP): 2-5 μg/mg; western blot: 1:2,000- 1:10,000
• accession no.: NP_001460.1
• shipped in: wet ice
• storage temp.: 2-8°C
• target post-translational modification: unmodified
• Gene Information: rabbit ... Ku70(2547)

Description

Immunogen

The epitope recognized by PLA0263 maps to a region between residue 500 and 550 of human Lupus Ku autoantigen protein p70 using the numbering given in entry NP_001460.1 (GeneID 2547).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

Ku70 is the 70 kDa subunit of the lupus Ku autoantigen. The lupus Ku autoantigen was identified in individuals with systemic lupus erythematosus (SLE) and related disorders. The Ku antigen is a heterodimer of Ku70 and Ku80. The Ku70/Ku80 complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P12956].

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable