N3501

β-Nicotinamide mononucleotide

≥95% (HPLC)

• Synonym(s): β-NMN, β-Nicotinamide ribose monophosphate, NMN, Nicotinamide ribotide, Nicotinamide-1-ium-1-β-D-ribofuranoside 5′-phosphate
• Empirical Formula (Hill Notation): C₁₁H₁₅N₂O₈P
• CAS Number: 1094-61-7
• Molecular Weight: 334.22
• Beilstein: 3570187
• EC Number: 214-136-5
• MDL number: MFCD00038748
• UNSPSC Code: 41106305
• PubChem Substance ID: 24897645
• NACRES: NA.51

Properties

• Quality Level: 200
• Assay: ≥95% (HPLC); ≥95% (spectrophotometric assay)
• form: powder
• storage temp.: −20°C
• SMILES string: C[C@H]1[C@@H](C)[C@@H](O[C@@H]1COP(O)([O-])=O)[n+]2cccc(c2)C(N)=O
• InChI: 1S/C13H19N2O6P/c1-8-9(2)13(21-11(8)7-20-22(17,18)19)15-5-3-4-10(6-15)12(14)16/h3-6,8-9,11,13H,7H2,1-2H3,(H3-,14,16,17,18,19)/t8-,9+,11+,13+/m0/s1
• InChI key: YYNOOWWEYJELSF-SEMCEJNYSA-N

Description

General description

β-Nicotinamide mononucleotide (β-NMN) is an intermediate in the nicotinamide phosphoribosyltransferase (NAMPT)-catalyzed biosynthesis of nicotinamide adenine dinucleotide (NAD+). NAMPT mediates the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to produce β-NMN. β-NMN adenyltransferase subsequently converts β-NMN to NAD+.

Application

β-Nicotinamide mononucleotide (NMN) is used to study binding motifs within RNA aptamers and ribozyme activation processes involving β-nicotinamide mononucleotide (β-NMN)-activated RNA fragments.

Other Notes

Note: This is the common form of NMN. Do not confuse it with α-NMN.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable
• Personal Protective Equipment: dust mask type N95 (US), Eyeshields, Gloves