H2393
HEPES sodium salt hydrate
≥99% (titration)
Synonym(s):
N-(2-Hydroxyethyl)piperazine-N′-(2-ethanesulfonic acid) hemisodium salt
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About This Item
Linear Formula:
C8H17N2O4SNa
CAS Number:
Molecular Weight:
260.29
EC Number:
MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
Recommended Products
Quality Level
Assay
≥99% (titration)
form
powder
useful pH range
6.8-8.2
7.5
pKa
7.5
solubility
water: 500 mg/mL, clear, colorless to faintly yellow
storage temp.
room temp
SMILES string
O.[Na+].OCCN1CCN(CC1)CCS([O-])(=O)=O
InChI
1S/C8H18N2O4S.Na.H2O/c11-7-5-9-1-3-10(4-2-9)6-8-15(12,13)14;;/h11H,1-8H2,(H,12,13,14);;1H2/q;+1;/p-1
InChI key
ZNJHFNUEQDVFCJ-UHFFFAOYSA-M
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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The mechanisms of action of endogenous modulatory ligands of connexin channels are largely unknown. Previous work showed that protonated aminosulfonates (AS), notably taurine, directly and reversibly inhibit homomeric and heteromeric channels that contain Cx26, a widely distributed connexin, but not
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