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GW22774

Sigma-Aldrich

Anti-GHRL (ab2) antibody produced in chicken

affinity isolated antibody, buffered aqueous solution

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

chicken

Quality Level

200

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

species reactivity

mouse, human, rat

technique(s)

indirect ELISA: suitable
western blot: suitable

NCBI accession no.

NP_067463.2

UniProt accession no.

Q9EQX0

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... GHRL(51738)
mouse ... Ghrl(58991)

Immunogen

Immunogen Sequence: GI # 19224664, sequence 38-49
Synthetic peptide sequence of ghrelin (Mus musculus).

Application

Anti-GHRL (ab2) antibody produced in chicken is suitable for indirect ELISA and western blotting analysis at a dilution of 1:500, for tissue or cell staining at a dilution of 1:200.

Biochem/physiol Actions

Ghrelin (GHRL), an orexigenic peptide, is primarily produced and secreted by the gastrointestinal tract. Its expression is correlated with tumor depth and tumor differentiation. It also plays an important role in tumor growth in esophageal squamous cell carcinoma (ESCC). Ghrelin secretion is changed during the onset and after the start of insulin therapy in children with type 1 diabetes. It may act as a good predictor of changes in glucose and metabolic control.

Physical form

Solution in phosphate buffered saline containing 0.02% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

Certificates of Analysis (COA)

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Flavia Prodam et al.
The Journal of clinical endocrinology and metabolism, 99(4), E599-E607 (2014-01-21)
Ghrelin secretion is altered at the onset and after the start of insulin therapy in children with type 1 diabetes. Contemporary regulation of acylated ghrelin (AG), unacylated ghrelin (UAG), and obestatin (OBST) remains undefined in this disease. It is unknown
Itaru Omoto et al.
Anticancer research, 34(6), 2727-2733 (2014-06-13)
Ghrelin, an orexigenic peptide, is primarily produced and secreted by the gastrointestinal tract. As far as we are aware of, there is no evidence of ghrelin expression in esophageal squamous cell carcinoma (ESCC). Two hundred and ten patients with ESCC

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