D7011
Deoxyribonucleic acid sodium salt from human placenta
Type XIII
Synonym(s):
hpDNA, DNA
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About This Item
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type
Type XIII
form
powder
storage temp.
2-8°C
InChI
1S/C15H31N3O13P2/c16-13-1-7(20)11(28-13)5-25-32(21,22)31-9-3-15(18)29-12(9)6-26-33(23,24)30-8-2-14(17)27-10(8)4-19/h7-15,19-20H,1-6,16-18H2,(H,21,22)(H,23,24)
InChI key
AWBASQCACWFTGD-UHFFFAOYSA-N
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General description
Deoxyribonucleic acid (DNA) from placenta and its methylation pattern is indicative of anomalies in the fetal growth. Tobacco smoking during pregnancy favors methylation and epigenetic modulation of placental DNA.
Application
Deoxyribonucleic acid sodium salt from human placenta has been used:
- as a standard for optimization of digestion followed by high-performance liquid chromatography (HPLC) and mass spectroscopy
- as a standard for ultra violet (UV) spectrophotometer measurements
- in polymerase chain reaction (PCR) assay and for standard curve generation for human papillomavirus type 6 quantification
Human placenta DNA (hpDNA) is a natural DNA used in studies of DNA binding anticancer agents and DNA binding agents that modulate DNA structure and function. Human placenta DNA is also used in physicochemical studies of DNA behavior in solution.
Storage Class Code
13 - Non Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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