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Key Documents

AV49246

Sigma-Aldrich

Anti-PRIM2 antibody produced in rabbit

IgG fraction of antiserum

Synonym(s):

Anti-MGC75142, Anti-PRIM2A, Anti-Primase, DNA, polypeptide 2 (58 kDa), Anti-RP3-401D24.1, Anti-p58

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

IgG fraction of antiserum

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

37 kDa

species reactivity

human

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_000938

UniProt accession no.

Q5JU42

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... PRIM2(5558)

Immunogen

Synthetic peptide directed towards the middle region of human PRIM2

Application

Anti-PRIM2 antibody produced in rabbit is suitable for western blotting at a concentration of 5.0μg/ml.

Biochem/physiol Actions

PRIM2 is a DNA primase that acts as DNA-directed RNA polymerase and synthesizes small RNA primers. These primers, termed Okazaki fragments are crucial for the replication of lagging DNA strand.

Sequence

Synthetic peptide located within the following region: QDFLKDSQLQFEAISDEEKTLREQEIVASSPSLSGLKLGFKSIYKPPFAS

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC18630

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A Shiratori et al.
Genomics, 28(2), 350-353 (1995-07-20)
DNA primase is an essential replication protein that catalyzes the synthesis of oligoribonucleotide primers. DNA primase, consisting of two subunits (p49 and p58), plays a key role in both the initiation of DNA replication and the synthesis of Okazaki fragments

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