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401676

Sigma-Aldrich

Sodium hydrogencarbonate

−40-+140 mesh, ≥95%

Synonym(s):

Sodium bicarbonate

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About This Item

Linear Formula:
NaHCO3
CAS Number:
144-55-8
Molecular Weight:
84.01
Beilstein:
4153970
EC Number:
205-633-8
MDL number:
MFCD00003528
UNSPSC Code:
12352302
PubChem Substance ID:
329755935
NACRES:
NA.55

Quality Level

100

Assay

≥95%

form

powder or crystals

impurities

2-5% Na2CO3

particle size

−40-+140 mesh

pKa (25 °C)

(1) 6.37, (2) 10.25 (carbonic acid)

density

2.16 g/mL at 25 °C (lit.)

SMILES string

[Na+].OC([O-])=O

InChI

1S/CH2O3.Na/c2-1(3)4;/h(H2,2,3,4);/q;+1/p-1

InChI key

UIIMBOGNXHQVGW-UHFFFAOYSA-M

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General description

Sodium hydrogencarbonate commonly known as sodium bicarbonate is a white crystalline solid or powder. A study of the crystalline structure shows that the bicarbonate ion has C2v symmetry. Ruthenium catalyzed hydrogenation of sodium bicarbonate to form sodium formate has been reported.

Application

Sodium hydrogencarbonate (sodium bicarbonate) may be used in the following processes:
  • As an alkalizing agent for treating metabolic acidosis.
  • For buffering local anesthetics (LA).
  • To facilitate the oxidation of styrene and cyclohexene.
  • As a medium to fabricate graphene hydrogel.

Storage Class Code

13 - Non Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Sigma-Aldrich

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Sodium bicarbonate

The crystal structure of sodium bicarbonate.
Sass RL and Scheuerman RF.
Acta Crystallographica, 15(1), 77-81 (1962)
Effect of Sodium Bicarbonate-buffered Lidocaine on the Success of Inferior Alveolar Nerve Block for Teeth with Symptomatic Irreversible Pulpitis: A Prospective, Randomized Double-blind Study.
Saatchi M, et al.
Journal of Endodontics, 41(1), 33-35 (2015)
Graphene aerogel prepared by thermal evaporation of graphene oxide suspension containing sodium bicarbonate.
Yang S, et al.
Journal of Material Chemistry A, 3(15), 7950-7958 (2015)
Sodium bicarbonate assisted oxidation, by H2O2, of styrene and cyclohexene using polymer grafted dioxidomolybdenum (VI) complex as a catalyst.
Maurya MR and Kumar N.
J. Mol. Catal. A: Chem., 406, 204-212 (2015)
Shay P McGuinness et al.
Critical care medicine, 41(7), 1599-1607 (2013-05-21)
Cardiac surgery-associated acute kidney injury occurs in up to 50% of patients and is associated with increased mortality and morbidity. This study aimed to discover if perioperative urinary alkalinization with sodium bicarbonate infusion reduces the prevalence of cardiac surgery-associated acute
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