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Key Documents

D0806

Sigma-Aldrich

Diethylamine

BioXtra

Synonym(s):

N,N-Diethylamine, N-ethyl-ethanamine, DEA, Diethamine, Diethyl amine

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About This Item

Linear Formula:
(C2H5)2NH
CAS Number:
Molecular Weight:
73.14
Beilstein:
605268
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.21

vapor density

2.5 (vs air)

Quality Level

vapor pressure

14.14 psi ( 55 °C)
180 mmHg ( 20 °C)
3.51 psi ( 20 °C)

product line

BioXtra

Assay

≥97.5% (GC)

form

liquid

autoignition temp.

594 °F

expl. lim.

10.1 %

impurities

<0.0005% Phosphorus (P)

ign. residue

<0.1%

refractive index

n20/D 1.385 (lit.)

bp

55 °C (lit.)

mp

−50 °C (lit.)

solubility

H2O: 1 M at 20 °C, clear, colorless

density

0.707 g/mL at 25 °C (lit.)

anion traces

chloride (Cl-): <0.05%
sulfate (SO42-): <0.05%

cation traces

Al: <0.0005%
Ca: <0.0005%
Cu: <0.0005%
Fe: <0.0005%
K: <0.005%
Mg: <0.0005%
NH4+: <0.05%
Na: <0.005%
Pb: <0.001%
Zn: <0.0005%

functional group

amine

SMILES string

CCNCC

InChI

1S/C4H11N/c1-3-5-4-2/h5H,3-4H2,1-2H3

InChI key

HPNMFZURTQLUMO-UHFFFAOYSA-N

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General description

Diethylamine (DEA) is an organic base and a weak σ-donor ligand. It plays the role of a bond-breaking agent in a novel ELISA (enzyme-linked immunosorbent assay technique for measuring the avidity index (AI) of IgG-anti-PT (Immunoglobulin G-anti-pertussis toxin) antibodies.

Application

Diethylamine has been used to prepare a high-pH elution solution in combination with sodium deoxycholate, which was employed during the immunoabsorption of postsynaptic density (PSD) proteins.

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Oral - Acute Tox. 4 Inhalation - Eye Dam. 1 - Flam. Liq. 2 - Skin Corr. 1A - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

3 - Flammable liquids

WGK

WGK 1

Flash Point(F)

-14.8 °F - closed cup

Flash Point(C)

-26 °C - closed cup

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Inhibited Catalyst Activation in (N-Heterocyclic carbene) PdCl2 (diethylamine) Complexes by Intramolecular Hydrogen Bonding.
Chen MT, et al.
Organometallics, 30(24), 6770-6773 (2011)
Alex-Mikael Barkoff et al.
Vaccine, 30(48), 6897-6902 (2012-09-18)
Pertussis toxin (PT) is a specific virulence factor of Bordetella pertussis and it is included in all acellular pertussis vaccines (aP). Although immunity after infection seems to persist longer than that after vaccination, the exact mechanism(s) is not known. Primary
A practical and highly efficient protocol for multicomponent synthesis of β-phosphonomalononitriles and 2-amino-4H-chromen-4-yl phosphonates using diethylamine as a novel organocatalyst.
Kulkarni MA, et al.
Comptes Rendus Chimie, 15(9), 745-752 (2012)
Yen Yun-Hong et al.
Molecular & cellular proteomics : MCP, 10(10), M110-M110 (2011-07-01)
Postsynaptic density (PSD) is a protein supramolecule lying underneath the postsynaptic membrane of excitatory synapses and has been implicated to play important roles in synaptic structure and function in mammalian central nervous system. Here, PSDs were isolated from two distinct
Katina S S Dossou et al.
Journal of chromatography. A, 1216(44), 7450-7455 (2009-06-26)
A polysaccharide-based chiral stationary phase (Sepapak-4), with cellulose tris(4-chloro-3-methylphenylcarbamate) as chiral selector, has been investigated in liquid chromatography (LC). Its enantioresolution power was evaluated towards 13 basic amino-drugs with widely different structures and polarities, using polar organic mobile phases. After

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