61382

D-α-Hydroxyglutaric acid disodium salt

analytical standard

• Synonym(s): D-2HG, (R)-2-Hydroxypentanedioic acid disodium salt, Disodium (R)-2-hydroxyglutarate
• Linear Formula: C₅H₆O₅Na₂
• CAS Number: 103404-90-6
• Molecular Weight: 192.08
• Beilstein: 5318041
• MDL number: MFCD00069573
• UNSPSC Code: 41116107

Properties

• grade: analytical standard
• Assay: ≥98.0% (GC)
• optical activity: [α]/D 8.5±1.5°, c = 1 in 0.1 M NaOH
• shelf life: limited shelf life, expiry date on the label
• application(s): clinical testing
• format: neat
• storage temp.: 2-8°C
• SMILES string: [Na].O[C@H](CCC(O)=O)C(O)=O
• InChI: 1S/C5H8O5.2Na/c6-3(5(9)10)1-2-4(7)8;;/h3,6H,1-2H2,(H,7,8)(H,9,10);;/q;2*+1/p-2/t3-;;/m1../s1
• InChI key: DZHFTEDSQFPDPP-HWYNEVGZSA-L

Description

Application

D-α-Hydroxyglutaric acid disodium salt may be used as an analytical standard for the quantification of 2-hydroxyglutarate (2HG) and 2-hydroxyglutarate (2HG) enantiomers in human serum samples of patients with isocitrate dehydrogenase (IDH) mutated tumors using chromatography-based techniques.

Safety Information

• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable