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Phosphamidon

PESTANAL®, analytical standard

Synonym(s):

2-Chloro-N,N-diethyl-3-(dimethylphosphono)crotonic amide

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About This Item

Empirical Formula (Hill Notation):
C10H19ClNO5P
CAS Number:
Molecular Weight:
299.69
Beilstein:
8323501
EC Number:
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

analytical standard

Quality Level

product line

PESTANAL®

shelf life

limited shelf life, expiry date on the label

technique(s)

HPLC: suitable
gas chromatography (GC): suitable

application(s)

agriculture
cleaning products
cosmetics
environmental
food and beverages
personal care

format

neat

storage temp.

2-8°C

SMILES string

CCN(CC)C(=O)\C(Cl)=C(\C)OP(=O)(OC)OC

InChI

1S/C10H19ClNO5P/c1-6-12(7-2)10(13)9(11)8(3)17-18(14,15-4)16-5/h6-7H2,1-5H3/b9-8+

InChI key

RGCLLPNLLBQHPF-CMDGGOBGSA-N

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General description

Phosphamidon is a neurotoxic organophosphorus insecticide.

Application

Phosphamidon may be used as a reference standard in the analysis of phosphamidon in tobacco samples using gas chromatography coupled with triple quadrupole mass spectrometry (GC-MS/MS).
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Legal Information

PESTANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Signal Word

Danger

Hazard Classifications

Acute Tox. 1 Inhalation - Acute Tox. 2 Dermal - Acute Tox. 2 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Muta. 2

Storage Class Code

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Certificates of Analysis (COA)

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Male reproductive toxicity of phosphamidon: histopathological changes in epididymis.
Akbarsha MA and P Sivasamy
Indian Journal of Experimental Biology, 36(1), 34-38 (1998)
Comparative study of pesticide multi-residue extraction in tobacco for gas chromatography-triple quadrupole mass spectrometry.
Lee M-J, et al.
Journal of Chromatography A, 1187(1-2), 25-33 (2008)
S G Suke et al.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 41(9), 765-768 (2008-09-30)
The effect of N-acetylcysteine, a thiolic antioxidant, on attenuation of phosphamidon-induced oxidative stress and immune dysfunction was evaluated in adult male Wistar rats weighing 200-250 g. Rats were divided into four groups, 8 animals/group, and treated with phosphamidon, N-acetylcysteine or
Sandhya Rabindranathan et al.
Journal of hazardous materials, 102(2-3), 217-229 (2003-09-16)
The photocatalytic degradation of a small concentration of an organo-phosphorous (OP) insecticide phosphamidon, in water, on ZnO and TiO(2) is investigated. Of the two semiconductor oxides, TiO(2) is found to be more effective as a photocatalyst for this reaction. Several
Angela Rouvalis et al.
Ecotoxicology and environmental safety, 72(3), 828-833 (2008-11-11)
Rainwater samples from four municipalities located in Achaia Prefecture, Greece, were collected from March to September 2006. The toxic potency of pollutants present in 36 rainwater samples was tested using Daphnia pulex. The pesticide determination was conducted with GC-MS. Only

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