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Key Documents

00583

Sigma-Aldrich

Nitrous oxide

≥99.998%

Synonym(s):

Dinitrogen monoxide, Laughing gas

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About This Item

Empirical Formula (Hill Notation):
N2O
CAS Number:
Molecular Weight:
44.01
Beilstein:
8137358
MDL number:
UNSPSC Code:
12142100
PubChem Substance ID:
NACRES:
NA.22

vapor density

1.53 (15 °C, vs air)

vapor pressure

51.7 mmHg ( 21 °C)

Assay

≥99.998%

bp

−88 °C (lit.)

mp

−91 °C (lit.)

SMILES string

[O-][N+]#N

InChI

1S/N2O/c1-2-3

InChI key

GQPLMRYTRLFLPF-UHFFFAOYSA-N

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Application

Nitrous oxide can be used as:
  • A nitrogen donor to synthesize alkynyl and alkenyl substituted triazenes by coupling reaction with lithium amides and organomagnesium compounds.
  • A reagent to synthesize azoimidazolium dyes.

N2O can also be reacted with N-heterocyclic olefins (NHOs) to form electron-rich azo-bridged NHO dimers.

Packaging

pressure tin
filling pressure at 15°C: 11 bar; content (15°C, 1 bar): 11 l

Other Notes

Sales restrictions may apply

Signal Word

Danger

Hazard Statements

Hazard Classifications

Ox. Gas 1 - Press. Gas Liquefied gas - STOT SE 3

Target Organs

Central nervous system

Storage Class Code

2A - Gases

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Personal Protective Equipment

dust mask type N95 (US), Eyeshields, Gloves

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Synthesis of azoimidazolium dyes with nitrous oxide
Tskhovrebov AG, et al.
Angewandte Chemie (International Edition in English), 127, 1305-1308 (2015)
Yan Chen et al.
Anesthesiology, 118(6), 1322-1331 (2013-04-04)
Nitrous oxide inactivates methionine synthase and may lead to DNA damage and wound infection. By using single-cell gel electrophoresis (comet assay), the authors determined the effect of nitrous oxide on DNA damage in circulating leukocytes. In this double-blind, randomized controlled
M M R Jahangir et al.
Journal of contaminant hydrology, 152, 70-81 (2013-07-31)
Identification of specific landscape areas with high and low groundwater denitrification potential is critical for improved management of agricultural nitrogen (N) export to ground and surface waters and indirect nitrous oxide (N₂O) emissions. Denitrification products together with concurrent hydrogeochemical properties
Imke Kuiper et al.
Global change biology, 19(9), 2814-2825 (2013-04-30)
Nitrous oxide (N2 O) emissions from soils contribute significantly to global warming. Mitigation of N2 O emissions is severely hampered by a lack of understanding of its main controls. Fluxes can only partly be predicted from soil abiotic factors and
R L M Schils et al.
Animal : an international journal of animal bioscience, 7 Suppl 1, 29-40 (2012-10-04)
Herbivores are a significant source of nitrous oxide (N(2)O) emissions. They account for a large share of manure-related N(2)O emissions, as well as soil-related N(2)O emissions through the use of grazing land, and land for feed and forage production. It

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