10602361001
Roche
Plasmin, human
from human plasma
Synonym(s):
Plasmin
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About This Item
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biological source
human plasma
Quality Level
Assay
95% (electrophoresis)
form
suspension
specific activity
~8 units/mg protein (At 25 °C with Chromozym PL as the substrate.)
mol wt
Mr ~85 kDa
packaging
pkg of 0.5 mL (5 U)
manufacturer/tradename
Roche
optimum pH
8.9
shipped in
wet ice
General description
Inhibitors: DFP, PMSF, TLCK, leupeptin, aprotinin, soybean trypsin inhibitor, α1-antitrypsin, α2-macroglobulin, anti-thrombin III heparin, APMSF, and α2-antiplasmin
Fibrinolysin
Specificity
Serine endopeptidase that hydrolyzes peptide and ester bonds at the carboxylic side of Lys or Arg; more selective than trypsin.
Application
Human plasmin has been used as an oligopeptide substrate in peptidase inhibition assays.
Biochem/physiol Actions
Plasmin is a direct acting fibrinolytic enzyme present in blood. Its activity is independent of plasminogen presence during fibrinolysis. Plasmin is rapidly and irreversibly inhibited by α-2 antiplasmin.
Physical form
Suspension in 3.2 M ammonium sulfate solution
Preparation Note
Stabilizers: Human plasmin does not contain stabilizers.
Storage conditions (working solution): 2 to 8 °C
Diluted solution (pH 8.6) is stable at 2 to 8 °C for at least 1–2 weeks. For storage of dialyzed solution freezing in aliquots is recommended.
Storage conditions (working solution): 2 to 8 °C
Diluted solution (pH 8.6) is stable at 2 to 8 °C for at least 1–2 weeks. For storage of dialyzed solution freezing in aliquots is recommended.
Storage and Stability
Store at 2 to 8 °C. (Recommended form for storage is ammonium sulfate suspension 3.2 M, pH 8.6.)
Other Notes
For life science research only. Not for use in diagnostic procedures.
Disclaimer
RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Signal Word
Danger
Hazard Statements
Hazard Classifications
Eye Dam. 1 - Skin Corr. 1B
Storage Class Code
12 - Non Combustible Liquids
WGK
WGK 1
Flash Point(F)
No data available
Flash Point(C)
No data available
Certificates of Analysis (COA)
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R D Shlansky-Goldberg et al.
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