Skip to Content
Merck
All Photos(1)

Documents

3741

Millipore

Hemin Chloride

Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.

Synonym(s):

Hemin Chloride

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

CAS Number:
16009-13-5
MDL number:
MFCD00010726
UNSPSC Code:
12352202
NACRES:
NA.21

Quality Level

100

form

solid

manufacturer/tradename

Calbiochem®

storage condition

OK to freeze
protect from light

color

dark purple

solubility

0.1-1.0 M NaOH: soluble
1 N NH4OH: soluble

shipped in

ambient

storage temp.

15-25°C

InChI

1S/C34H34N4O4.Fe/c1-7-21-17(3)25-13-26-19(5)23(9-11-33(39)40)31(37-26)16-32-24(10-12-34(41)42)20(6)28(38-32)15-30-22(8-2)18(4)27(36-30)14-29(21)35-25;/h7-8,13-16H,1-2,9-12H2,3-6H3,(H4,35,36,37,38,39,40,41,42);/q;+3/p-2

InChI key

GGIDWJQWCUJYRY-UHFFFAOYSA-L

General description

Iron containing compound of porcine origin that can induce H2O2-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions. Induces heme-oxygenase-1 activity and reduces renal injury induced by mercuric compounds.
Iron-containing compound of porcine origin that can induce hydrogen peroxide-dependent lipid peroxidation. Reported to increase the number and size of myotubes and the frequency of myotube contractions.

Application


  • Porphyrins ameliorate spinocerebellar ataxia type 36 GGCCTG repeat expansion-mediated cytotoxicity: Discusses the therapeutic potentials of hemin chloride in neurological disorders, highlighting its role in mitigating cytotoxic effects associated with genetic mutations, significant for advancing neurodegenerative disease treatments (Hirayanagi K et al., 2021).

  • Indirect Quantification of Glyphosate by SERS Using an Incubation Process With Hemin as the Reporter Molecule: A Contribution to Signal Amplification Mechanism: Demonstrates the application of hemin chloride in enhancing signal detection in spectroscopic analysis, important for improving analytical methods in environmental and food sciences (López-Castaños KA et al., 2020).

Warning

Toxicity: Standard Handling (A)

Reconstitution

Unstable in solution; reconstitute just prior to use.

Analysis Note

homogeneous by TLC

Other Notes

Yonega, R., et al. 2000. Toxicol. Lett.116, 223.
Funanage, V.L., et al. 1989. J. Cell. Physiol.141, 591.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Kristine Y Tan et al.
The Analyst, 145(10), 3732-3741 (2020-04-30)
In an open microfluidic device, we investigate protein polyacrylamide gel electrophoresis (PAGE) separation performance on single-cell lysate. Single-cell protein electrophoresis is performed in a thin layer of polyacrylamide (PA) gel into which microwells are molded. Individual cells are isolated in

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service