1.05957

Manganese(IV) oxide

powder EMPLURA^®

• Synonym(s): Manganese(IV) oxide, Manganese dioxide, Pyrolusite
• Empirical Formula (Hill Notation): MnO₂
• CAS Number: 1313-13-9
• Molecular Weight: 86.94
• MDL number: MFCD00003463
• UNSPSC Code: 12352303
• EC Index Number: 215-202-6
• NACRES: NA.21

Properties

• Quality Level: 200
• product line: EMPLURA^®
• Assay: ≥89.0% (manganometric)
• form: powder
• potency: >3478 mg/kg LD₅₀, oral (Rat)
• impurities: ≤5% Substances insoluble in hydrochloric acid
• loss: ≤0.3% loss on drying, 105°C
• solubility: insoluble <0.001 g/L
• density: 5.21 g/cm³ at 21 °C
• bulk density: 600‑800 kg/m³
• anion traces: sulfate (SO₄^2-): ≤0.1%
• cation traces: Ba: ≤1.0%; Ca: ≤1.0%; Fe: ≤1.5%
• storage temp.: 2-30°C
• InChI: 1S/Mn.2O
• InChI key: NUJOXMJBOLGQSY-UHFFFAOYSA-N

Description

Application

• The chemically synthesized ageladine A-derivative LysoGlow84 stains lysosomes in viable mammalian brain cells and specific structures in the marine flatworm Macrostomum lignano.: This research highlights the use of a manganese-based synthetic derivative, LysoGlow84, which effectively stains lysosomes in mammalian brain cells and certain marine flatworms. The study underscores its significance in cellular biology and molecular imaging, providing a tool for detailed lysosomal studies in diverse biological systems (Mordhorst et al., 2015).

Analysis Note

Assay (manganometric): ≥ 89.0 %
Substances insoluble in hydrochloric acid: ≤ 5.0 %
Sulfate (SO₄): ≤ 0.1 %
Ba (Barium): ≤ 1.0 %
Ca (Calcium): ≤ 1.0 %
Fe (Iron): ≤ 1.5 %
Loss on Drying (105°C): ≤ 0.3 %

Legal Information

EMPLURA is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Pictograms: GHS07,GHS08
• Signal Word: Warning
• Hazard Statements: H302 + H332 - H373
• Precautionary Statements: P260 - P264 - P270 - P301 + P312 - P304 + P340 + P312 - P314
• Hazard Classifications: Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - STOT RE 2 Inhalation
• Target Organs: Brain
• Storage Class Code: 13 - Non Combustible Solids
• WGK: WGK 1
• Flash Point(F): does not flash
• Flash Point(C): does not flash