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T-078

Supelco

3,3′,5′-Triiodo-L-thyronine-13C6 (reverse T3-13C6)

100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®

Synonym(s):

3,3′,5′-Triiodo-L-thyronine-13C6 solution

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About This Item

Empirical Formula (Hill Notation):
13C6C9H12I3NO4
CAS Number:
1786403-77-7
Molecular Weight:
656.93
UNSPSC Code:
41116107
NACRES:
NA.24

grade

certified reference material

Quality Level

300

form

liquid

feature

(Snap-N-Spike®)

packaging

ampule of 1 mL

manufacturer/tradename

Cerilliant®

concentration

100 μg/mL in methanol with 0.1N NH3

technique(s)

gas chromatography (GC): suitable
liquid chromatography (LC): suitable

format

single component solution

storage temp.

−20°C

SMILES string

IC1=CC(O[13C]2=[13CH][13CH]=[13C](C[C@H](N)C(O)=O)[13CH]=[13C]2I)=CC(I)=C1O

InChI

1S/C15H12I3NO4/c16-9-3-7(4-12(19)15(21)22)1-2-13(9)23-8-5-10(17)14(20)11(18)6-8/h1-3,5-6,12,20H,4,19H2,(H,21,22)/t12-/m0/s1/i1+1,2+1,3+1,7+1,9+1,13+1

InChI key

HZCBWYNLGPIQRK-CXGLLCBXSA-N

General description

Reverse T3 or rT3 is a biologically inactive form of the thyroid hormone T3 and is produced in the body particularly during periods of stress. Under certain conditions such as fibromyalgia, liver disease, and chronic fatigue syndrome (CFS), more rT3 is produced which inhibits the desirable conversion of thyroxine (T4) to T3. This internal standard and Certified Spiking Solution® is suitable for quantitation of reverse T3 serum concentrations by LC-MS/MS to monitor impact of these and other diseases on thyroid hormone levels.

Legal Information

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany
CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation
Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

related product

Product No.
Description
Pricing

T-073

L-Thyroxine (T4) solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®

T-074

3,3′,5-Triiodo-L-thyronine (T3) solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®

T-075

3,3′,5′-Triiodo-L-thyronine (Reverse T3) solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®

T-076

L-Thyroxine-13C6 solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®

T-077

3,3′,5-Triiodo-L-thyronine-13C6 solution, 100 μg/mL in methanol with 0.1N NH3, ampule of 1 mL, certified reference material, Cerilliant®

Signal Word

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1

Target Organs

Eyes,Central nervous system

Storage Class Code

3 - Flammable liquids

WGK

WGK 2

Flash Point(F)

49.5 °F

Flash Point(C)

9.7 °C

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Protocols

Online Solid Phase Extraction and LC-MS Analysis of Thyroid Hormones in Human Serum

Thyroid hormones play critical roles in the regulation of biological processes, such as growth, metabolism, protein synthesis, and brain development. For a clinical laboratory, fast and reliable measurements of total hormone levels are important for the diagnosis and monitoring of thyroid diseases.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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