214914
N,N-Dimethylmethyleneiminium iodide
98%
Synonym(s):
N,N-Dimethylmethyleneammonium iodide, Eschenmoser’s salt
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About This Item
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Quality Level
Assay
98%
mp
219 °C (dec.) (lit.)
solubility
water: soluble 50 mg/mL, clear to slightly hazy, colorless to yellow
functional group
amine
SMILES string
[I-].C[N+](C)=C
InChI
1S/C3H8N.HI/c1-4(2)3;/h1H2,2-3H3;1H/q+1;/p-1
InChI key
VVDUZZGYBOWDSQ-UHFFFAOYSA-M
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General description
N,N-Dimethylmethyleneiminium iodide is useful reagent for many synthetic applications, especially aminomethylation and conversion of ketones to α,β−unsaturated enones.
Signal Word
Warning
Hazard Statements
Precautionary Statements
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
Target Organs
Respiratory system
Storage Class Code
11 - Combustible Solids
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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Chem. Abstr., 120, 190555b-190555b (1994)
Journal of the Chemical Society. Perkin Transactions 1, 3295-3295 (1992)
Synthetic Routes to Unsymmetrical Porphyrins.
Synthesis and Modifications of Porphyrinoids, 203-239 (2014)
The Journal of organic chemistry, 72(8), 3065-3075 (2007-03-16)
(-)-Merrilactone A [(-)-1], isolated from Illicium merrillianum in 2000, possesses neurite outgrowth activity in cultures of fetal rat cortical neurons, and, therefore, is expected to show therapeutic potential for the treatment of neurodegeneration associated with Alzheimer's and Parkinson's diseases. Apart
A new method using 2-chloro-4, 6-dimethoxy-1, 3, 5-triazine for facile elimination of dimethylamino group in Eschenmoser's methylenation for synthesis of a, ?-unsaturated esters.
Tetrahedron Letters, 54(13), 1753-1760 (2013)
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