117722
1-Adamantanecarbonyl chloride
95%
Synonym(s):
1-Adamantanecarboxylic acid chloride, 1-Chlorocarbonyladamantane
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About This Item
Empirical Formula (Hill Notation):
C11H15ClO
CAS Number:
Molecular Weight:
198.69
Beilstein:
389960
EC Number:
MDL number:
UNSPSC Code:
12352100
PubChem Substance ID:
NACRES:
NA.22
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Quality Level
Assay
95%
form
solid
bp
135-136 °C/10 mmHg (lit.)
mp
49-51 °C (lit.)
SMILES string
ClC(=O)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2
InChI
1S/C11H15ClO/c12-10(13)11-4-7-1-8(5-11)3-9(2-7)6-11/h7-9H,1-6H2/t7-,8+,9-,11-
InChI key
MIBQYWIOHFTKHD-KJZNFTALSA-N
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General description
1-Adamantanecarbonyl chloride on reaction with triethylammonium isopropylphosphite forms mixed anhydride, an efficient capping reagent for the hydrogen-phosphonate DNA synthesis. It is a good substrate for Friedel–Crafts acylation of anisole in the presence of indium metal.
Application
1-Adamantanecarbonyl chloride was used in the preparation of efficient amine-modified oligodeoxynucleotides for fabrication of DNA microarrays.
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Skin Corr. 1B
Supplementary Hazards
Storage Class Code
8A - Combustible corrosive hazardous materials
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
dust mask type N95 (US), Eyeshields, Gloves
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