PYCARD
PYD and CARD domain containing
Synonyms:
ASC, CARD5, TMS, TMS-1, TMS1
Species:
Human PYCARD (29108), Mouse Pycard (66824), Rat Pycard (282817), Zebrafish pycard (57923), dog PYCARD (489925), domestic cat PYCARD (101088449), cow PYCARD (282846), sheep PYCARD (101105208), Goat PYCARD (100861338), domestic guinea pig Pycard (100734858)
UniProtKB ID:
Gene ID:
- Human(29108) Summary: This gene encodes an adaptor protein that is composed of two protein-protein interaction domains: a N-terminal PYRIN-PAAD-DAPIN domain (PYD) and a C-terminal caspase-recruitment domain (CARD). The PYD and CARD domains are members of the six-helix bundle death domain-fold superfamily that mediates assembly of large signaling complexes in the inflammatory and apoptotic signaling pathways via the activation of caspase. In normal cells, this protein is localized to the cytoplasm; however, in cells undergoing apoptosis, it forms ball-like aggregates near the nuclear periphery. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
- Mouse(66824) PYD and CARD domain containing
- Rat(282817) PYD and CARD domain containing
- Zebrafish(57923) PYD and CARD domain containing
- dog(489925) PYD and CARD domain containing
- domestic cat(101088449) PYD and CARD domain containing
- cow(282846) PYD and CARD domain containing
- sheep(101105208) PYD and CARD domain containing
- Goat(100861338) PYD and CARD domain containing
- domestic guinea pig(100734858) PYD and CARD domain containing
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-ASC antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-ASC antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PYCARD antibody produced in rabbit, IgG fraction of antiserum,
Species Reactivity
human, mouse
Application
western blot
Anti-ASC/TMS1 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot