IL5
interleukin 5 (colony-stimulating factor, eosinophil)
Synonyms:
EDF, IL-5, TRF
Species:
Human IL5 (3567), Mouse Il5 (16191), Rat Il5 (24497), sheep IL5 (443350), domestic guinea pig Il5 (100135558), naked mole-rat Il5 (101719528), chicken IL5 (474360), cow IL5 (280825), Horse IL5 (100034199), domestic cat IL5 (493803)
UniProtKB ID:
Gene ID:
- Human(3567) Summary: This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 within a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31. [provided by RefSeq, Jul 2013]
- Mouse(16191) interleukin 5
- Rat(24497) interleukin 5
- sheep(443350) interleukin 5 (colony-stimulating factor, eosinophil)
- domestic guinea pig(100135558) interleukin 5
- naked mole-rat(101719528) interleukin 5 (colony-stimulating factor, eosinophil)
- chicken(474360) interleukin 5 (colony-stimulating factor, eosinophil)
- cow(280825) interleukin 5 (colony-stimulating factor, eosinophil)
- Horse(100034199) interleukin 5 (colony-stimulating factor, eosinophil)
- domestic cat(493803) interleukin 5 (colony-stimulating factor, eosinophil)
- dog(403790) interleukin 5 (colony-stimulating factor, eosinophil)
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Small Molecule - Antagonist
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Interleukin-5 antibody produced in goat, IgG fraction of antiserum, lyophilized powder,
Species Reactivity
human
Application
ELISA
neutralization
western blot
neutralization
western blot
Proteins
Product Number
Description
Species
Interleukin-5 from mouse, ≥97% (SDS-PAGE), recombinant, expressed in baculovirus infected Sf21 cells, lyophilized powder, suitable for cell culture,
Species
mouse
Interleukin-5 human, recombinant, expressed in baculovirus infected Sf21 cells, ≥97% (SDS-PAGE), lyophilized powder, suitable for cell culture,
Species
human
IL-5 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
human
IL-5 from mouse, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Species
mouse