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Activation of Sirt1/FXR Signaling Pathway Attenuates Triptolide-Induced Hepatotoxicity in Rats.

Frontiers in pharmacology (2017-05-26)
Jing Yang, Lixin Sun, Lu Wang, Hozeifa M Hassan, Xuan Wang, Phillip B Hylemon, Tao Wang, Huiping Zhou, Luyong Zhang, Zhenzhou Jiang
RESUMEN

Triptolide (TP), a diterpenoid isolated from

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Sigma-Aldrich
GW4064, ≥97% (HPLC)