A human immunodeficiency syndrome caused by mutations in CARMIL2.

A human immunodeficiency syndrome caused by mutations in CARMIL2.

Nature communications (2017-01-24)

T Schober, T Magg, M Laschinger, M Rohlfs, N D Linhares, J Puchalka, T Weisser, K Fehlner, J Mautner, C Walz, K Hussein, G Jaeger, B Kammer, I Schmid, M Bahia, S D Pena, U Behrends, B H Belohradsky, C Klein, F Hauck

PMID28112205

RESUMEN

Human T-cell function is dependent on T-cell antigen receptor (TCR) and co-signalling as evidenced by immunodeficiencies affecting TCR-dependent signalling pathways. Here, we show four human patients with EBV

MATERIALES

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V9131

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MP0025

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AB3201

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CP06

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HPA041402

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Anti-CARMIL2 antibody produced in rabbit, Prestige Antibodies^® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution