- Acetylene functionalized BODIPY dyes and their application in the synthesis of activity based proteasome probes.
Acetylene functionalized BODIPY dyes and their application in the synthesis of activity based proteasome probes.
Bioorganic & medicinal chemistry letters (2007-09-25)
Martijn Verdoes, Ulrik Hillaert, Bogdan I Florea, Myra Sae-Heng, Martijn D P Risseeuw, Dmitri V Filippov, Gijsbert A van der Marel, Herman S Overkleeft
PMID17888658
RESUMEN
The synthesis of three acetylene functionalized BODIPY dyes is described. These dyes are used to fluorescently modify an azido functionalized epoxomicin analogue employing the Huisgen 1,3-dipolar cycloaddition, resulting in a panel of fluorescent epoxomicin derived proteasome probes.
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