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Ceftriaxone-induced hemolytic anemia: case report and review of literature.

Journal of pediatric hematology/oncology (2014-06-01)
Michael S Northrop, Hemant S Agarwal
RESUMEN

Ceftriaxone is a frequently used empiric antibiotic in children. Acute hemolysis is a rare side effect of ceftriaxone therapy associated with a high mortality rate. A 14-year-old boy suffering from Crohn disease developed bacterial pneumonia that was treated with ceftriaxone. We report successful management of ceftriaxone-induced hemolytic anemia (CIHA) in this patient and review the CIHA literature in pediatric patients. Early recognition of CIHA with prompt discontinuation of ceftriaxone therapy may have a beneficial role in reduction of high mortality seen in these patients.

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Sigma-Aldrich
Ceftriaxone disodium salt hemi(heptahydrate), third-generation cephalosporin antibiotic
USP
Ceftriaxone sodium, United States Pharmacopeia (USP) Reference Standard
Supelco
Ceftriaxone Sodium, Pharmaceutical Secondary Standard; Certified Reference Material
Ceftriaxone sodium, European Pharmacopoeia (EP) Reference Standard