- Novel aminoethylbiphenyls as 5-HT7 receptor ligands.
Novel aminoethylbiphenyls as 5-HT7 receptor ligands.
Bioorganic & medicinal chemistry letters (2007-04-10)
Magalie Paillet-Loilier, Frédéric Fabis, Alban Lepailleur, Ronan Bureau, Sabrina Butt-Gueulle, François Dauphin, Aurélien Lesnard, Catherine Delarue, Hubert Vaudry, Sylvain Rault
PMID17419056
RESUMEN
The synthesis of a series of aminoethylbiphenyls as novel 5-HT(7) receptor ligands is described. The novel derivatives exhibit high affinity for the 5-HT(7) receptor with selectivity toward 5-HT(1A) receptor.