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The palladium-catalyzed cross-coupling reactions of trifluoroethyl iodide with aryl and heteroaryl boronic acid esters.

Chemical communications (Cambridge, England) (2012-07-13)
Apeng Liang, Xinjian Li, Dongfeng Liu, Jingya Li, Dapeng Zou, Yangjie Wu, Yusheng Wu
RESUMEN

The cross-coupling reactions of 1,1,1-trifluoro-2-iodoethane with aryl and heteroaryl boronic acid esters have been successfully achieved. The new protocol allows for a convenient introduction of trifluoroethyl groups into a variety of aryl and heteroaryl moieties under mild conditions.

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Sigma-Aldrich
1,1,1-Trifluoro-2-iodoethane, 99%