- Cytotoxic glycosides from the roots of Weigela x "Bristol Ruby".
Cytotoxic glycosides from the roots of Weigela x "Bristol Ruby".
Fitoterapia (2019-06-17)
Duc Hung Nguyen, Anne-Claire Mitaine-Offer, Sveva Maroso, Anna-Maria Papini, Thomas Paululat, Pierre-Simon Bellaye, Bertrand Collin, Odile Chambin, Marie-Aleth Lacaille-Dubois
PMID31202889
RESUMEN
Seven oleanane-type glycosides were extracted and isolated by various chromatographic methods from the roots of Weigela x "Bristol Ruby" (1-7), six previously undescribed (1-6) and a known one (7). Their structures were assigned by spectroscopic analysis mainly 2D NMR and mass spectrometry (ESIMS). Selected triterpenoid glycosides (1-3, 6, 7) displayed a good cytotoxic activity against a mouse colon cancer cell line CT26.
MATERIALES