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TPO

thyroid peroxidase

Sinónimos:
MSA, TDH2A, TPX
Especie:
ID UniProtKB:
ID del gen:
  • Human(7173) Summary: This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined. [provided by RefSeq, May 2011]
  • Mouse(22018) thyroid peroxidase
  • Rat(54314) thyroid peroxidase
  • cow(525013) thyroid peroxidase
  • naked mole-rat(101704548) thyroid peroxidase
  • domestic guinea pig(100723704) thyroid peroxidase
  • chicken(776120) thyroid peroxidase
  • domestic cat(101098706) thyroid peroxidase
  • dog(403521) thyroid peroxidase

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ELISA

Referencia del producto
Descripción
Especie
Human TPO / Thyroid Peroxidase ELISA Kit, for serum, plasma, cell culture supernatants and urine,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TPO antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry

western blot
Anti-TPO antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-TPO (Thyroid Peroxidase) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM368, purified immunoglobulin,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-TPO antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-Thyroid Peroxidase Antibody, clone 3C4A4, Rabbit Monoclonal, ,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Methimazole, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Methimazole, analytical standard,
Especie
human
Methimazole, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Methimazole, VETRANAL®, analytical standard,
Especie
human
2-Mercapto-1-methylimidazole, ≥99%,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
Thrombopoietin, TPO (Thrombopoietin, Mpl-ligand, MGDF) stimulates the proliferation & maturation of megakaryocytes & promotes increased circulating levels of platelets in vivo.,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human TPO,
Especie
human