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MilliporeSigma

TLR8

toll-like receptor 8

Sinónimos:
CD288
Especie:
ID UniProtKB:
ID del gen:
  • Human(51311) Summary: The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung and peripheral blood leukocytes, and lies in close proximity to another family member, TLR7, on chromosome X. [provided by RefSeq, Jul 2008]
  • Mouse(170744) toll-like receptor 8
  • Rat(684440) toll-like receptor 8
  • Zebrafish(100334317) toll-like receptor 8
  • dog(100684828) toll-like receptor 8
  • Horse(100054367) toll-like receptor 8
  • domestic cat(493658) toll-like receptor 8
  • domestic guinea pig(100713058) toll-like receptor 8
  • naked mole-rat(101726643) toll-like receptor 8
  • Domestic Rabbit(100328930) toll-like receptor 8
  • cow(532262) toll-like receptor 8
  • sheep(554259) toll-like receptor 8
  • Goat(100860909) toll-like receptor 8

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-TLR8 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-TLR8 antibody produced in rabbit, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunocytochemistry

western blot
Monoclonal Anti-TLR8 antibody produced in mouse, clone 4C6, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
ANTI-MOUSE TLR8 (C-TERM) antibody produced in rabbit, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
mouse
Aplicación
immunohistochemistry
western blot
Anti-TLR8 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Tlr8,
Especie
mouse
MISSION® esiRNA, targeting human TLR8,
Especie
human