STAT5B
signal transducer and activator of transcription 5B
Sinónimos:
STAT5
Especie:
Human STAT5B (6777), Mouse Stat5b (20851), Rat Stat5b (25126), domestic guinea pig Stat5b (100716532), naked mole-rat Stat5b (101722721), cow STAT5B (282376), sheep STAT5B (101122961), chicken STAT5B (395556), domestic cat STAT5B (101090663), dog STAT5B (490969)
ID UniProtKB:
ID del gen:
- Human(6777) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein mediates the signal transduction triggered by various cell ligands, such as IL2, IL4, CSF1, and different growth hormones. It has been shown to be involved in diverse biological processes, such as TCR signaling, apoptosis, adult mammary gland development, and sexual dimorphism of liver gene expression. This gene was found to fuse to retinoic acid receptor-alpha (RARA) gene in a small subset of acute promyelocytic leukemias (APLL). The dysregulation of the signaling pathways mediated by this protein may be the cause of the APLL. [provided by RefSeq, Jul 2008]
- Mouse(20851) signal transducer and activator of transcription 5B
- Rat(25126) signal transducer and activator of transcription 5B
- domestic guinea pig(100716532) signal transducer and activator of transcription 5B
- naked mole-rat(101722721) signal transducer and activator of transcription 5B
- cow(282376) signal transducer and activator of transcription 5B
- sheep(101122961) signal transducer and activator of transcription 5B
- chicken(395556) signal transducer and activator of transcription 5B
- domestic cat(101090663) signal transducer and activator of transcription 5B
- dog(490969) signal transducer and activator of transcription 5B
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ELISA
Referencia del producto
Descripción
Especie
Cell-Based ELISA for detecting phospho-STAT5 (pTyr694) in cultured cell lines, 96 assays,
Especie
human
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-STAT5B Antibody, Upstate®, from rabbit,
Reactividad de especies
human, mouse
Aplicación
western blot
Anti-acetyl STAT5B (Lys701) Antibody, from rabbit, purified by affinity chromatography,
Reactividad de especies
human
Aplicación
dot blot
western blot
western blot
Anti-STAT5B (ab2) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
dog, horse, human, mouse, pig, rabbit, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-STAT5B Antibody, clone 2G13 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
bovine, feline, human, monkey, porcine, rat
Aplicación
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
ANTI-STAT5B antibody produced in mouse, clone 2D1, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
immunofluorescence
immunohistochemistry
western blot
Proteins
Referencia del producto
Descripción
Especie