STAT5A
signal transducer and activator of transcription 5A
Sinónimos:
MGF, STAT5
Especie:
Human STAT5A (6776), Mouse Stat5a (20850), Rat Stat5a (24918), dog STAT5A (490968), Horse STAT5A (100052904), domestic cat STAT5A (101090913), cow STAT5A (282375), sheep STAT5A (443419), naked mole-rat Stat5a (101723770), domestic guinea pig Stat5a (100716811)
ID UniProtKB:
ID del gen:
- Human(6776) Summary: The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq, Jul 2008]
- Mouse(20850) signal transducer and activator of transcription 5A
- Rat(24918) signal transducer and activator of transcription 5A
- dog(490968) signal transducer and activator of transcription 5A
- Horse(100052904) signal transducer and activator of transcription 5A
- domestic cat(101090913) signal transducer and activator of transcription 5A
- cow(282375) signal transducer and activator of transcription 5A
- sheep(443419) signal transducer and activator of transcription 5A
- naked mole-rat(101723770) signal transducer and activator of transcription 5A
- domestic guinea pig(100716811) signal transducer and activator of transcription 5A
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ELISA
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone 8-5-2, clone 8-5-2, Upstate®, from mouse,
Reactividad de especies
bovine, human, mouse, rat, sheep
Aplicación
western blot
Anti-Phospho-STAT5A-Y694 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone 94-10C-9-10C-2, rabbit monoclonal, clone 94-10C-9-10C-2, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-phospho-STAT5A/B (Ser726/Ser731) Antibody, serum, Upstate®,
Reactividad de especies
human, mouse, rat
Aplicación
western blot
Anti-phospho-STAT5A/B (Tyr694/699) Antibody, clone A11W, rabbit monoclonal, culture supernatant, clone A11W, from rabbit,
Reactividad de especies
bovine, chimpanzee, human, mouse, rat
Aplicación
western blot