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SLC6A2

solute carrier family 6 (neurotransmitter transporter), member 2

Sinónimos:
NAT1, NET, NET1, SLC6A5
Especie:
ID UniProtKB:
ID del gen:
  • Human(6530) Summary: This gene encodes a member of the sodium:neurotransmitter symporter family. This member is a multi-pass membrane protein, which is responsible for reuptake of norepinephrine into presynaptic nerve terminals and is a regulator of norepinephrine homeostasis. Mutations in this gene cause orthostatic intolerance, a syndrome characterized by lightheadedness, fatigue, altered mentation and syncope. Alternatively spliced transcript variants encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
  • Mouse(20538) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Rat(83511) solute carrier family 6 (neurotransmitter transporter), member 2
  • chicken(395458) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • dog(487272) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(493768) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Horse(100061346) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic cat(101099605) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • cow(282363) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(443100) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • sheep(101116078) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • Domestic Rabbit(100328959) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • naked mole-rat(101716834) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
  • domestic guinea pig(100723578) solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2

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Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
4,4′-Diaminodiphenylmethane, ≥97.0% (GC),
Especie
mouse, rat
Nefazodone hydrochloride, ≥98% (HPLC), solid,
Especie
human
Nefazodone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Amoxapine, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Amoxapine, 1.0 mg/mL in methanol, certified reference material, Cerilliant®,
Especie
human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-Norepinephrine Antibody, serum, Chemicon®,
Reactividad de especies
human, rat
Aplicación
immunohistochemistry
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot
Anti-SLC6A2, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-SLC6A2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, canine, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot
Anti-Norepinephrine Transporter Antibody, Chemicon®, from rabbit,
Reactividad de especies
mouse, rat
Aplicación
ELISA
western blot

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
Desipramine hydrochloride, ≥98% (TLC), powder,
Especie
human
Desipramine hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human
Debrisoquine sulfate, ,
Especie
human
Atomoxetine hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Maprotiline hydrochloride solution, 1.0 mg/mL in methanol (as free base), ampule of 1 mL, certified reference material, Cerilliant®,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SLC6A2,
Especie
human

Small Molecule - Substrate

Referencia del producto
Descripción
Especie
Guanethidine monosulfate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Bretylium tosylate, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Guanethidine monosulfate, British Pharmacopoeia (BP) Reference Standard,
Especie
human