SIRT1
sirtuin 1
Sinónimos:
SIR2L1
Especie:
Human SIRT1 (23411), Mouse Sirt1 (93759), Rat Sirt1 (309757), domestic guinea pig Sirt1 (100717014), naked mole-rat Sirt1 (101720282), Domestic Rabbit SIRT1 (100349271), cow SIRT1 (613629), sheep SIRT1 (101102956), Zebrafish sirt1 (797132), chicken SIRT1 (423646) ...Más
ID UniProtKB:
ID del gen:
- Human(23411) Summary: This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008]
- Mouse(93759) sirtuin 1
- Rat(309757) sirtuin 1
- domestic guinea pig(100717014) sirtuin 1
- naked mole-rat(101720282) sirtuin 1
- Domestic Rabbit(100349271) sirtuin 1
- cow(613629) sirtuin 1
- sheep(101102956) sirtuin 1
- Zebrafish(797132) sirtuin (silent mating type information regulation 2 homolog) 1
- chicken(423646) sirtuin 1
- dog(489012) sirtuin 1
- domestic cat(101087610) sirtuin 1
- Horse(100072571) sirtuin 1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
ELISA
Referencia del producto
Descripción
Especie
Small Molecule - Activator
Referencia del producto
Descripción
Especie
Activity Assay
Referencia del producto
Descripción
Especie
Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anticuerpo anti-SIRT1, clon 10E4, clone 10-E-4, from mouse,
Reactividad de especies
human, mouse
Aplicación
ChIP
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-SIRT1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
immunohistochemistry
Anti-SIRT1 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-SIRT1 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Aplicación
western blot
Monoclonal Anti-SIRT1 antibody produced in mouse, clone 7B7, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Small Molecule - Inhibitor
Proteins
Referencia del producto
Descripción
Especie
Sirt1 human, recombinant, expressed in E. coli, N-terminal histidine tagged, ≥90% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human
SIRT1, active, His tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Especie
human