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MilliporeSigma

SETD2

SET domain containing 2

Sinónimos:
HBP231, HIF-1, HIP-1, HYPB, KMT3A, SET2, p231HBP
Especie:
ID UniProtKB:
ID del gen:
  • Human(29072) Summary: Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II. [provided by RefSeq, Aug 2008]
  • Mouse(235626) SET domain containing 2
  • Rat(316013) SET domain containing 2
  • Zebrafish(794199) SET domain containing 2
  • Horse(100064888) SET domain containing 2
  • domestic cat(101085029) SET domain containing 2
  • dog(476643) SET domain containing 2
  • chicken(420404) SET domain containing 2
  • cow(539860) SET domain containing 2
  • naked mole-rat(101719404) SET domain containing 2
  • domestic guinea pig(100719166) SET domain containing 2

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-SETD2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-SETD2 antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
human
Aplicación
immunohistochemistry
western blot
Anti-SETD2 antibody produced in rabbit, ,
Reactividad de especies
human, mouse, rat
Aplicación
immunofluorescence
western blot
Monoclonal Anti-SETD2 antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL9956, purified immunoglobulin, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Anti-SETD2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
canine, human, mouse, pig
Aplicación
ELISA
western blot

Proteins

Referencia del producto
Descripción
Especie
Set2 human, recombinant, expressed in E. coli, ≥75% (SDS-PAGE),
Especie
human
SETD2 active human, recombinant, expressed in E. coli, ≥70% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SETD2,
Especie
human
MISSION® esiRNA, targeting mouse Setd2,
Especie
mouse