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SERPINI1

serpin peptidase inhibitor, clade I (neuroserpin), member 1

Sinónimos:
PI12, neuroserpin
Especie:
ID UniProtKB:
ID del gen:
  • Human(5274) Summary: This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
  • Mouse(20713) serine (or cysteine) peptidase inhibitor, clade I, member 1
  • Rat(116459) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • Zebrafish(557627) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • dog(478684) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • domestic cat(101090383) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • Horse(100057410) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • chicken(425002) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • Domestic Rabbit(100341797) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • naked mole-rat(101716288) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • domestic guinea pig(100733658) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • cow(509976) serpin peptidase inhibitor, clade I (neuroserpin), member 1
  • sheep(101122566) serpin peptidase inhibitor, clade I (neuroserpin), member 1

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-SERPINI1, (C-terminal) antibody produced in mouse, clone 1E10, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
western blot
Anti-SERPINI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
Anti-Neuroserpin antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
chimpanzee, human, mouse, rat
Aplicación
ELISA
western blot
Anti-SERPINI1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunohistochemistry
Monoclonal Anti-SERPINI1 antibody produced in mouse, clone 1D10, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunohistochemistry

western blot

Proteins

Referencia del producto
Descripción
Especie
Neuroserpin human, recombinant, expressed in E. coli, ≥96% (SDS-PAGE), ≥96% (HPLC), suitable for cell culture,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human SERPINI1,
Especie
human
MISSION® esiRNA, targeting mouse Serpini1,
Especie
mouse