PTRF
polymerase I and transcript release factor
Sinónimos:
CAVIN, CAVIN1, CGL4, cavin-1
Especie:
Human PTRF (284119), Mouse Ptrf (19285), Rat Ptrf (287710), chicken PTRF (396006), domestic cat PTRF (101096121), dog PTRF (490966), cow PTRF (538457), sheep PTRF (101110525), naked mole-rat Ptrf (101721546), domestic guinea pig Ptrf (100717539)
ID UniProtKB:
ID del gen:
- Human(284119) Summary: This gene encodes a protein that enables the dissociation of paused ternary polymerase I transcription complexes from the 3' end of pre-rRNA transcripts. This protein regulates rRNA transcription by promoting the dissociation of transcription complexes and the reinitiation of polymerase I on nascent rRNA transcripts. This protein also localizes to caveolae at the plasma membrane and is thought to play a critical role in the formation of caveolae and the stabilization of caveolins. This protein translocates from caveolae to the cytoplasm after insulin stimulation. Caveolae contain truncated forms of this protein and may be the site of phosphorylation-dependent proteolysis. This protein is also thought to modify lipid metabolism and insulin-regulated gene expression. Mutations in this gene result in a disorder characterized by generalized lipodystrophy and muscular dystrophy. [provided by RefSeq, Nov 2009]
- Mouse(19285) polymerase I and transcript release factor
- Rat(287710) polymerase I and transcript release factor
- chicken(396006) polymerase I and transcript release factor
- domestic cat(101096121) polymerase I and transcript release factor
- dog(490966) polymerase I and transcript release factor
- cow(538457) polymerase I and transcript release factor
- sheep(101110525) polymerase I and transcript release factor
- naked mole-rat(101721546) polymerase I and transcript release factor
- domestic guinea pig(100717539) polymerase I and transcript release factor
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PTRF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-PTRF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reactividad de especies
human
Aplicación
immunofluorescence
Anti-PTRF antibody produced in rabbit, IgG fraction of antiserum,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
western blot
Anti-PTRF antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-PTRF antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot