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PTGER4

prostaglandin E receptor 4 (subtype EP4)

Sinónimos:
EP4, EP4R
Especie:
ID UniProtKB:
ID del gen:
  • Human(5734) Summary: The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor can activate T-cell factor signaling. It has been shown to mediate PGE2 induced expression of early growth response 1 (EGR1), regulate the level and stability of cyclooxygenase-2 mRNA, and lead to the phosphorylation of glycogen synthase kinase-3. Knockout studies in mice suggest that this receptor may be involved in the neonatal adaptation of circulatory system, osteoporosis, as well as initiation of skin immune responses. [provided by RefSeq, Jul 2008]
  • Mouse(19219) prostaglandin E receptor 4 (subtype EP4)
  • Rat(84023) prostaglandin E receptor 4 (subtype EP4)
  • domestic guinea pig(100192398) prostaglandin E receptor 4 (subtype EP4)
  • Domestic Rabbit(100009081) prostaglandin E receptor 4 (subtype EP4)
  • naked mole-rat(101723705) prostaglandin E receptor 4 (subtype EP4)
  • cow(282331) prostaglandin E receptor 4 (subtype EP4)
  • sheep(101104343) prostaglandin E receptor 4 (subtype EP4)
  • sheep(443222) prostaglandin E receptor 4 (subtype EP4)
  • chicken(427183) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(101094734) prostaglandin E receptor 4 (subtype EP4)
  • domestic cat(100169968) prostaglandin E receptor 4 (subtype EP4)
  • dog(403589) prostaglandin E receptor 4 (subtype EP4)

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Small Molecule - Agonist

Referencia del producto
Descripción
Especie
Dinoprostone, United States Pharmacopeia (USP) Reference Standard,
Especie
human
Dinoprostone, European Pharmacopoeia (EP) Reference Standard,
Especie
human
Prostaglandin E1, ≥98% (HPLC), synthetic,
Especie
human, mouse
Prostaglandin E1, γ-irradiated, powder, BioXtra, suitable for cell culture,
Especie
human, mouse
Prostaglandin E1, synthetic, powder, BioReagent, suitable for cell culture,
Especie
human, mouse

Small Molecule - Antagonist

Referencia del producto
Descripción
Especie
Prostaglandin E1, ≥98% (HPLC), synthetic,
Especie
human, mouse
Prostaglandin E1, γ-irradiated, powder, BioXtra, suitable for cell culture,
Especie
human, mouse
Prostaglandin E1, synthetic, powder, BioReagent, suitable for cell culture,
Especie
human, mouse
Prostaglandin E2, synthetic, powder, BioReagent, suitable for cell culture,
Especie
human, mouse
Prostaglandin E2, ≥93% (HPLC), synthetic,
Especie
mouse, human

Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PTGER4 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
western blot
Anti-EP4 Prostaglandin Receptor antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reactividad de especies
canine, human
Aplicación
ELISA
western blot
Anti-PE2R4 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human
Aplicación
ELISA
immunofluorescence

western blot

Small Molecule - Mixed Agonist/Antagonist

Referencia del producto
Descripción
Especie
Prostaglandin E2, ≥93% (HPLC), synthetic,
Especie
mouse, human
Indomethacin, 98.5-100.5% (in accordance with EP),
Especie
human, mouse, rat

Proteins

Referencia del producto
Descripción
Especie
ChemiScreen Membrane Preparation
Recombinant Human EP4 Prostanoid Receptor
, Human EP4 GPCR membrane preparation for Radioligand binding Assays & GTPγS binding.,
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PTGER4,
Especie
human
MISSION® esiRNA, targeting mouse Ptger4,
Especie
mouse