PLOD2
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
Sinónimos:
LH2, TLH
Especie:
Human PLOD2 (5352), Mouse Plod2 (26432), Rat Plod2 (300901), Zebrafish plod2 (100036767), Horse PLOD2 (100061030), chicken PLOD2 (424882), dog PLOD2 (485702), domestic cat PLOD2 (101085741), domestic guinea pig Plod2 (100735218), naked mole-rat Plod2 (101708679) ...Más
ID UniProtKB:
ID del gen:
- Human(5352) Summary: The protein encoded by this gene is a membrane-bound homodimeric enzyme that is localized to the cisternae of the rough endoplasmic reticulum. The enzyme (cofactors iron and ascorbate) catalyzes the hydroxylation of lysyl residues in collagen-like peptides. The resultant hydroxylysyl groups are attachment sites for carbohydrates in collagen and thus are critical for the stability of intermolecular crosslinks. Some patients with Ehlers-Danlos syndrome type VIB have deficiencies in lysyl hydroxylase activity. Mutations in the coding region of this gene are associated with Bruck syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
- Mouse(26432) procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
- Rat(300901) procollagen lysine, 2-oxoglutarate 5-dioxygenase 2
- Zebrafish(100036767) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
- Horse(100061030) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
- chicken(424882) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
- dog(485702) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
- domestic cat(101085741) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
- domestic guinea pig(100735218) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
- naked mole-rat(101708679) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
- cow(533642) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
- sheep(101103613) procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2
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Antibodies
Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PLOD2 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
bovine, dog, horse, human, mouse, pig, rabbit, rat
Aplicación
immunohistochemistry
western blot
western blot
Anti-PLOD2 antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
western blot