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MilliporeSigma

PKM

pyruvate kinase, muscle

Sinónimos:
CTHBP, OIP3, PK3, PKM2, TCB, THBP1
Especie:
ID UniProtKB:
ID del gen:
  • Human(5315) Summary: This gene encodes a protein involved in glycolysis. The encoded protein is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. This protein has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. This protein has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of this protein in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported. [provided by RefSeq, May 2011]
  • Mouse(18746) pyruvate kinase, muscle
  • Rat(25630) pyruvate kinase, muscle
  • cow(512571) pyruvate kinase, muscle
  • sheep(101109180) pyruvate kinase, muscle
  • Domestic Rabbit(100008676) pyruvate kinase, muscle
  • naked mole-rat(101721034) pyruvate kinase, muscle
  • domestic guinea pig(100736056) pyruvate kinase, muscle
  • Horse(100063687) pyruvate kinase, muscle
  • domestic cat(101092521) pyruvate kinase, muscle
  • dog(403874) pyruvate kinase, muscle

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
Anti-PKM2 Antibody, clone 1B2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse, rat
Aplicación
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-PKM1 Antibody, clone 1B15 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reactividad de especies
human, mouse
Aplicación
affinity binding assay
immunohistochemistry

western blot
Anti-PKM antibody produced in rabbit, ,
Reactividad de especies
human
Aplicación
immunofluorescence
western blot
Anti-PKM1 Antibody, serum, from rabbit,
Reactividad de especies
human, mouse
Aplicación
immunohistochemistry
western blot
Anti-PKM2 Antibody, serum, from rabbit,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
western blot

Proteins

Referencia del producto
Descripción
Especie
PKM1 active human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
MISSION® esiRNA, targeting human PKM,
Especie
human